BS Microbiology and Molecular Genetics (Morning)

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MMG 637: IMMUNOHAEMATOLOGY

Overview

THEORY: General aspects of hematology, processes of hematopoises; Features and functioning of polymorpho- and mononuclear phagocytic system; Mechanism of intra and extracellular killing of pathogens; Antigen processing and presentation; Humoral mediations of natural immunity; Role of T-helper population in humoral and cellular immunity; Involvement of immunocompetent cells in delayed hypersensitivity, immunity to intracellular parasites and tumors and in transplant rejection; Methods for detection of cellular immunity. Separation and identification of lymphocytes and macrophages. Applications of CD markers and monoclonal antibodies. Flow cytometry and cell sorting; Complications and consequences of blood transfusions. Blood complement therapy.
PRACTICAL: Determination of cellular immunity. Identification of lymphocytes, general tests for hematology, Flow cytometry.


Credit hours/ Marks:- 2+1

1. Eva, D. Q. 2000. Immunohematology: Principles and Practice, Lippincot Williams and Wilkins, M.D.
2. Kimball, J. W. 2000.Introduction to Immunology, MacMillan Publishers,N.Y.
3. Rose, N. and Fahey, F. 2002. Manual of Clinical Laboratory Immunology,American Society for Microbiology, Washington, D.C.

Will be updated soon